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How To Reverse Aging and Stimulate Collagen With Topical Peptides

Collagen loss is a natural part of aging, and it's something that all of us have to deal with. However, when you're trying to keep your skin looking young and fresh, collagen loss can be a real challenge. Fortunately, topical peptides are an effective way to stimulate collagen production in order to help prevent this loss as well as other signs of aging.

What is Collagen?

Collagen is a natural protein found in the human body. It's made up of amino acids and is responsible for holding together our skin, bones, muscles, tendons, and ligaments. As we age, our bodies produce less collagen, which can lead to wrinkles and other signs of aging.

There are 28 different types of collagen that have been identified, each categorized by its amino acid composition.

Collagen type I is found in the skin and other soft tissues; it makes up cartilage and bone as well as the walls of blood vessels. 

Collagen type II makes up cartilage and reticular fibers; it's also the main component of tendons and ligaments. 

Collagen type III makes up reticular fibers in your body; these fibers form part of connective tissue supporting organs like your heart and lungs.

Collagen type IV forms the basis of cell basement membranes. It can be found in tissues containing type I collagen.

Collagen type IV is found in tissues containing type I collagen.

If the body struggles to produce collagen efficiently, it can manifest in a range of health problems, including chondrodysplasia (which causes dwarfism), Ehlers-Danlos syndrome (a connective tissue disorder that affects the skin, ligaments, and blood vessels), Alport syndrome (an inherited kidney disease), Bethlem myopathy (a rare neuromuscular disorder) and some cases of osteoporosis (thinning of the bones). 

In some cases, it may also contribute to arterial aneurysms (bulges in arteries) or intervertebral disc disease (disks between vertebrae breaking down).

What Are The Benefits Of Collagen?


Collagen is especially important for preventing wrinkles when it comes to your skin because it helps keep it firm and flexible. It can also make your hair look shiny and healthy by keeping it strong and thickening it at the roots.

Taking hydrolyzed collagen supplements can help you maintain your body's collagen production and prevent age-related bone and joint problems. They're made from collagen that has been broken down into smaller pieces (hydrolyzed) so that they can be absorbed by the body more easily. This means you don't have to eat pounds of meat every day just to get enough protein!

Hair Growth

Collagen has been shown to be capable of helping with hair growth. Collagen can act as an antioxidant and fight damage caused by free radicals—that's one reason why it's good for your skin and joints.

When you apply collagen-based products like hair serums or lotions directly onto your scalp or into your hair follicles, they help fill in those spaces where your natural collagen has broken down over time. This helps keep your hair healthy so that it doesn't fall out when you comb or brush it!

Joint Health

Collagen supplementation has been found to be effective in improving joint mobility, reducing pain and inflammation, and improving the overall quality of life for those suffering from osteoarthritis and rheumatoid arthritis.

Bone Health

According to a review published in Dental Materials Journal, collagen peptides derived from the skin, bones, and scales of fish may help regulate the proliferation of osteoblasts. Osteoblasts are cells that help to build bones and repair fractures and other injuries.

Healthy Foods That Help Boost Your Collagen Production

Collagen is a protein that's found in the skin and connective tissues, which means it's super important for keeping your body healthy. When collagen levels are low, you can experience dry skin, wrinkles, and joint pain.

There are several ways you can encourage your body to produce more collagen; you just need to make sure you're getting enough of the right foods:

Bone Broth

Bone broth is a great source of amino acids that are necessary for collagen production and healing. It also contains chondroitin sulfate and glucosamine, which are two natural anti-inflammatory compounds that help reduce pain and inflammation in joints. Bone broth is also rich in calcium and magnesium, which are both essential for healthy bones.

Bone broth is made by simmering bones for at least 24 hours in the water, and it's full of calcium, magnesium, and protein—all three of which help your body produce collagen. You can find bone broth in most grocery stores or health food stores, but if you want a more natural option that won't leave you with a bunch of added ingredients, try making your own!


Chicken is especially great for boosting collagen production because it contains high levels of protein and B vitamins, which help you grow hair and nails. And if that wasn't enough, chicken is also full of iron—an essential nutrient that helps prevent anemia and boosts energy levels.

Fish & Shellfish

Fish and shellfish are rich in omega-3 fatty acids, which are thought to be essential for maintaining healthy collagen levels. Omega-3s are also known to help reduce inflammation, so if you have acne or breakouts from time to time, this could be a good way to get rid of them.

Citrus Fruits

Citrus fruits are loaded with vitamin C, which helps build new skin cells and promote collagen production. It also helps strengthen blood vessels and capillaries while also helping your body produce more collagen.


Beans contain a lot of protein and fiber, so they help you feel full while also helping to keep your blood sugar levels stable. This helps your body produce more collagen—and fight against wrinkles!

Cosmetic Products & Procedures to Restore or Increase Collagen Production

Creams & serums

Topical creams and serums are a great way to target collagen production. A good place to start is with a daily moisturizer that contains vitamin C or hyaluronic acid. Vitamin C helps with collagen production by encouraging the growth of new cells, while hyaluronic acid helps keep existing cells healthy. You can also use a serum that uses retinol or vitamin A to encourage collagen production in the skin.

If your issue is deeper than just surface wrinkles, try a prescription-strength retinol cream called Tretinoin or Retin-A Micro gel. These medications are typically used for acne treatment but can also help smooth out deep wrinkles on your face and body.

Topical peptides

There is also an inexpensive and effective solution for collagen production and wrinkle reduction: topical peptide. Peptides are small chains of amino acids that help your body produce more collagen. They are also effective at reducing the effects of aging on your skin by increasing the rate at which cells divide and grow.

The two most commonly used peptides are palmitoyl tetrapeptide-7, which has been shown to reduce wrinkles by 50% after four weeks of use (1), and palmitoyl tripeptide-1, which promotes the production of collagen (2). These peptides work by mimicking the structure of a protein that stimulates your body's natural collagen production.

Palmitoyl tetrapeptide-7 is a great example of an ingredient that can help with this process. This topical peptide is known to have anti-aging benefits and has been shown to reduce the number of wrinkles on the face.

Another peptide, palmitoyl tripeptide 1, has also been shown to help with collagen production and wrinkle reduction. It has been proven effective at reducing the appearance of fine lines and wrinkles and improving skin elasticity.

When used topically on your face or neck area for an extended period of time (like overnight), peptides can help increase the amount of collagen present in those areas. This reduces wrinkles and fine lines over time by adding volume back into your skin without needing expensive procedures like Botox injections or surgical procedures like a facelift!


Microneedling, also known as Collagen Induction Therapy (CIT) or Derma Rolling, is a minimally invasive treatment that helps to improve collagen production in the skin. It's also used to treat acne scars, fine lines and wrinkles, hyperpigmentation, stretch marks, surgical scars, and more.

Microneedling works by creating tiny puncture wounds in the skin. This stimulates your body's natural healing process and causes a release of growth factors that encourage collagen production.

Dermal and facial fillers

Dermal and facial fillers are used to smooth out wrinkles, plump up lips, and create a more youthful appearance. Dermal fillers are injected into the deeper layers of the skin, while facial fillers go right under the top layer of the skin.

Skin resurfacing lasers

Skin resurfacing lasers are a type of surgical procedure that uses intense light to treat wrinkles, scars, and other signs of sun damage. The laser beams break up the damaged tissue and stimulate new skin growth where they touch the skin. This process can take anywhere from eight weeks to several months depending on how deep the laser treatment goes.

Chemical peels

Chemical peels are a popular way to remove dead skin and encourage collagen production. A chemical peel is a process that involves the application of a strong acid to the skin, which causes it to burn and peel off. The acid also stimulates the new growth of healthy, smooth skin.

Frequently Asked Questions

How do peptides stimulate collagen production?

Peptides are found naturally in the body, but they can also be added to skin care products to help boost collagen production. They work by stimulating fibroblasts (cells) in the dermis, which are responsible for producing collagen. When you apply peptides to your skin, these cells begin to produce more collagen and other essential proteins that make up healthy skin tissue.

The best way to maximize these effects is to use a cream or serum with high concentrations of peptides at least once per day—preferably twice—and always after cleansing so your pores are open and ready to absorb nutrients from the product.

Are topical peptides safe to use?

Topical peptides are safe to use when they're used properly. The most important thing is to make sure that you get the right product for your skin.

  • First, make sure that you're using a product that is free of harmful chemicals and fillers. You should also go over the ingredients list with your physician to make sure that you're not allergic to any of them.
  • Second, always patch test the product on a small area of your skin before applying it over large areas. If your skin reacts poorly after a few days, discontinue use immediately.
  • Third, talk to your doctor if you have concerns about applying topical peptide products on sensitive areas like your face or neck (where creams can seep into your body through pores).

How long does it take for my skin to start looking better? 

It can take anywhere from one week to three months for you to notice any changes in the amount of collagen in your skin. The exact length of time depends on your body's natural ability to produce collagen and the strength of the product that you're using.

What is the difference between topical peptides and injectables?

Topical peptides are applied to the top of your skin, while injectables are injected deep into your skin. Topical peptides can be used as a part of a skincare routine, or in conjunction with other products such as moisturizers. Injectables (like Botox) require a doctor's prescription and are used to reduce wrinkles and fine lines.


The bottom line is that collagen is essential for keeping your skin looking young, and topical peptides can help you build it up. They’re easy to use, they don’t take much time, and they give amazing results. 

It's also important to remember that topical peptides should be used in addition to other treatments for your skin—not as a replacement for them. They aren't going to make miracles happen overnight, but they'll definitely help!